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A colorimetric granzyme B and caspase-8 substrate
Ac-IEPD-pNA is a colorimetric substrate for granzyme B and caspase-8. Granzyme B and caspase-8 preferentially bind to and cleave the Ile-Glu-Pro-Asp (IEPD) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of granzyme B and caspase-8 activity.
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