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  • [Leu31,Pro34] Neuropeptide Y (human) (trifluoroacetate salt)
[Leu31,Pro34] Neuropeptide Y (human) (trifluoroacetate salt)的可视化放大

[Leu31,Pro34] Neuropeptide Y (human) (trifluoroacetate salt)

An NPY receptor agonist

原价
¥2587-4875
价格
2070-3900
[Leu31,Pro34] Neuropeptide Y (human) (trifluoroacetate salt)的二维码

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  • 货号: ajcx17758
  • CAS: N/A
  • 别名: Leu31,Pro34 NPY
  • 分子式: C189H284N54O56S?XCF3COOH
  • 分子量: 4240.7
  • 纯度: >98%
  • 溶解度: Water: 1 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

[Leu31,Pro34] Neuropeptide Y (NPY) is an agonist of the NPY receptors Y1 and Y5 with Ki values of 0.11 and 0.17 nM, respectively, for human and 0.08 and 0.18 nM, respectively, for rhesus monkey receptors. It reduces forskolin-induced cAMP accumulation in L-M(TK-) cells expressing human and rat Y4 receptors (EC50s = 29.5 and 2.95 nM, respectively). It also binds to rhesus monkey Y2 and mouse Y6 receptors (Kis = 410 and 9.7 nM, respectively). In vitro, [Leu31,Pro34] NPY increases cellular protein mass by 25% in rat ventricular cardiomyocytes when used at a concentration of 10 nM. In vivo, [Leu31,Pro34] NPY (0.7-7 nmol, i.c.v.) increases food intake in rats.

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