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  2. Caspase
  3. Ac-VDVAD-CHO (trifluoroacetate salt)
  • Ac-VDVAD-CHO (trifluoroacetate salt)
Ac-VDVAD-CHO (trifluoroacetate salt)的可视化放大

Ac-VDVAD-CHO (trifluoroacetate salt)

A caspase-2, caspase-3, and caspase-7 inhibitor

原价
￥1625-4062
价格
￥ 1300-3250
Ac-VDVAD-CHO (trifluoroacetate salt)的二维码

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  • 库存: 现货
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  • 货号: ajcx18052
  • CAS: N/A
  • 别名: Ac-Val-Asp-Val-Ala-Asp-CHO
  • 分子式: C23H37N5O10?XCF3COOH
  • 分子量: 543.6
  • 纯度: >98%
  • 溶解度: Water: 1 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Ac-VDVAD-CHO is an inhibitor of caspase-2, -3, and -7 (Kis = 3.5, 1, and 7.5 nM, respectively). It inhibits caspase-2 and -3 in cell-based assays with IC50 values of 1,334 and 346 nM, respectively. Ac-VDVAD-CHO (3 μM) inhibits increases in alkaline phosphatase and caspase-2 and -3 activity induced by human recombinant bone morphogenic protein 4 (BMP4) in MC3T3-E1 murine bone marrow stromal cells. It also inhibits BMP4-induced cell cycle arrest at the G0/G1 phase in MC3T3-E1 cells.

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