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A caspase-3 fluorogenic substrate
Mca-VDQMDGW-K(Dnp)-NH2 is a substrate for caspase-3. Upon cleavage by caspase-3, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify caspase-3 activity. Mca displays excitation/emission maxima of 328/420 nm, respectively.
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