A hydroxy fatty acid
3-hydroxy Heptadecanoic acid is a hydroxylated fatty acid. It is a component of LPS in several species of Gram-negative bacteria.1,2 Levels of 3-hydroxy heptadecanoic acid are decreased in the feces of patients with Crohn's disease.
|1. Weintraub, A., Larsson, B.E., and Lindberg, A.A. Chemical and immunochemical analyses of Bacteroides fragilis lipopolysaccharides. Infect. Immun. 49(1), 197-201 (1985).|2. Uhlig, S., Neg?rd, M., Heldal, K.K., et al. Profiling of 3-hydroxy fatty acids as environmental markers of endotoxin using liquid chromatography coupled to tandem mass spectrometry. J. Chromatogr. A 1434, 119-236 (2016).|3. De La Cochetiere, M.F., Rouge, C., Szponar, B., et al. 3-Hydroxy fatty acids in faeces of patients with Crohn's disease or ulcerative colitis as a non-invasive diagnostic approach. Microb. Ecol. Health Dis. 19(1), 1-6 (2007).
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