A neuropeptide with diverse biological activities
1-Palmitoyl-2-12-OAHSA-3-oleoyl-sn-glycerol is a triacylglycerol that contains palmitic acid , the fatty acid ester of hydroxy fatty acids (FAHFA) 12-OASHA , and oleic acid at the sn-1, sn-2, and sn-3 positions, respectively. It is an endogenous triacylglycerol that has been found in the lipid extract of mouse adipose tissue.1 FAHFA-containing triacylglycerol levels are greater than 100-fold higher than non-esterified FAHFAs in mouse adipose tissues, indicating that triacylglycerols act as intracellular storage reservoirs for FAHFAs.
|1. Tan, D., Ertunc, M.E., Konduri, S., et al. Discovery of FAHFA-containing triacyglycerols and their metabolic regulation. J. Am. Chem. Soc. 141(22), 8798-8806 (2019).
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