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  • (±)-Ibuprofen-d3
(±)-Ibuprofen-d3的可视化放大

(±)-Ibuprofen-d3

An Analytical Reference Standard

原价
¥387-5000
价格
310-4000
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  • 货号: ajcx20872
  • CAS: 121662-14-4
  • 别名: 氘代布洛芬,(±)-Ibuprofen-d3
  • 分子式: C13H15D3O2
  • 分子量: 209.3
  • 纯度: >98%
  • 溶解度: DMF: >45 mg/ml,DMSO: >50 mg/ml,Ethanol: >60 mg/ml,PBS (pH 7.2): >2 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Ibuprofen-d3 contains three deuterium atoms. It is intended for use as an internal standard for the quantification of ibuprofen by GC- or LC-mass spectrometry. Ibuprofen is a non-selective, reversible COX inhibitor. The IC50 values for human recombinant COX-1 and -2 are 2.6 and 1.53 µM, respectively.1 The Ki value for ovine COX-1 and -2 is 9 µM.2



1.Barnett, J., Chow, J., Ives, D., et al.Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus systemBiochim Biophys. Acta.1209(1)130-139(1994) 2.Johnson, J.L., Wimsatt, J., Buckel, S.D., et al.Purification and characterization of prostaglandin H synthase-2 from sheep placental cotyledonsArch. Biochem. Biophys.324(1)26-34(1995)

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