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  • D-Lysine lactam
D-Lysine lactam的可视化放大

D-Lysine lactam

A chiral building block

原价
¥712-5025
价格
570-4020
D-Lysine lactam的二维码

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  • 货号: ajcx22326
  • CAS: 28957-33-7
  • 别名: (R)-3-氨基-2-己内酰胺
  • 分子式: C6H12N2O
  • 分子量: 128.2
  • 纯度: >98%
  • 溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 10 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

D-Lysine lactam is a chiral building block.1,2 It has been used in the synthesis of a chiral antibiotic synthetic intermediate, as well as in the stereoselective synthesis of neurokinin (NK) receptor antagonists.



1.Kumar, A., Bhashkar, B., Bhavsar, J., et al.Catalytic reduction: Efficient synthesis of chiral key intermediate of besifloxacin hydrochlorideDer Pharma Chemica7(9)297-3000(2015) 2.Gerspacher, M., Lewis, C., Ball, H.A., et al.Stereoselective preparation of N-[(R,R)-(E)-1-(3,4-dichlorobenzyl)-3- (2-oxoazepan-3-yl)carbamoyl]allyl-N-methyl-3,5-bis(trifluoromethyl)benzamide, a potent and orally active dual neurokinin NK(1)/NK(2) receptor antagonistJ. Med. Chem.46(16)3508-3513(2003)

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