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  • Prostaglandin F2α-d9
Prostaglandin F2α-d9的可视化放大

Prostaglandin F2α-d9

A neuropeptide with diverse biological activities

原价
¥787-2825
价格
630-2260
Prostaglandin F2α-d9的二维码

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  • 货号: ajcx23354
  • CAS: N/A
  • 别名: Dinoprostd9
  • 分子式: C20H25D9O5
  • 分子量: 363.5
  • 纯度: >98%
  • 溶解度: DMF: 100 mg/ml,DMSO: 100 mg/ml,Ethanol: 100 mg/ml,PBS (pH 7.2): 1 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Prostaglandin F-d9 (PGF-d9) contains nine deuterium atoms at the 17, 17', 18, 18', 19, 19', 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of PGF by GC- or LC-mass spectrometry. PGF is a widely distributed PG occurring in many species.1,2,3 It causes contraction of vascular, bronchial, intestinal, and myometrial smooth muscle, and also exhibits potent luteolytic activity.1 PGF exerts its receptor mediated physiological activity at 50-100 nM.1 Maximal ovine myometrial contraction can be achieved at 125 nM PGF in vitro.4



1.Samuelsson, B., Goldyne, M., Granstr?m, E., et al.Prostaglandins and thromboxanesAnnu. Rev. Biochem.47997-1029(1978) 2.Speroff, L., and Ramwell, P.W.Prostaglandins in reproductive physiologyAm. J. Obstet. Gynecol.107(7)1111-1130(1970) 3.Watanabe, K., Iguchi, Y., Iguchi, S., et al.Stereospecific conversion of prostaglandin D2 to (5Z,13E)-(15S)-9α,-11β,15-trihydroxyprosta-5,13-dien-1-oic acid (9α,11β-prostaglandin F2) and of prostaglandin H2 to prostaglandin F2α by bovine lung prostaglandin F synthaseProc. Natl. Acad. Sci. U.S.A.83(6)1583-1587(1986) 4.Crankshaw, D.J., and Gaspar, V.Pharmacological characterization in vitro of prostanoid receptors in the myometrium of nonpregnant ewesJ. Reprod. Fertil.103(1)55-61(1995)

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