RS 09 (trifluoroacetate salt)

TLR4激动剂

原价

￥1312-15612

价格

￥ 1050-12490

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库存: 现货

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产品引用

货号: ajcx25078
CAS: N/A
别名: Ala-Pro-Pro-His-Ala-Leu-Ser, APPHALS
分子式: C31H49N9O9·XCF3COOH
分子量: 691.8
纯度: >98%
溶解度: DMF: 1 mg/ml,DMSO: 10 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 1 mg/ml
储存: Stored at -20°C
库存: 现货

Background

RS 09 is a peptide agonist of toll-like receptor 4 (TLR4).¹ It activates NF-κB in a concentration-dependent manner in a secreted alkaline phosphatase (SEAP) assay using TLR4-expressing HEK293 cells and induces NF-κB nuclear translocation in the same cells. It also induces cytokine secretion from RAW 264.7 cells. RS 09 (25 µg/animal) acts as an adjuvant in mice vaccinated with a KLH-conjugated X-15 antigen, with no antibodies produced in mice receiving RS 09 without the antigen.

1.Shanmugam, A., Rajoria, S., George, A.L., et al.Synthetic toll like receptor-4 (TLR-4) agonist peptides as a novel class of adjuvantsPLoS One7(2)e30839(2012)

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生命科学

有机化学

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材料科学

RS 09 (trifluoroacetate salt)

RS 09 (trifluoroacetate salt)详情

Background