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Sulfo-Cyanine5.5 azide 是一种近红外 (NIR) 荧光染料,是一种叠氮化物功能化的 Sulfo-Cyanine5.5 (Ex=678 nm, Em=694 nm)。
Sulfo-Cyanine5.5 is a water-soluble, hydrophilic fluorophore which possesses emission in far red area of the spectrum, an analog of Cy5.5?. As other cyanine dyes, sulfo-Cyanine5.5 has an outstanding molar extinction coefficient which gives rise to its bright fluorescence.
The molecule contains four sulfo groups that provide hydrophilicity and negative charge to the fluorophore - this minimizes non-specific binding.
The azide group of sulfo-Cyanine5.5 azide can be conjugated with terminal alkynes in the presence of copper(I) catalyst, or with cycloalkynes in copper free strain promoted reaction.
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