现货大促销,价格低至8折起,量大更优惠,详细咨询客服
全部分类
全部分类
  • 3-O-Methylquercetin
3-O-Methylquercetin的可视化放大

3-O-Methylquercetin

A flavone with diverse biological activities

原价
¥1525-3775
价格
1220-3020
3-O-Methylquercetin的二维码

所有产品仅用于科学研究,我们不为任何个人用途提供产品和服务

询价有惊喜,量大更优惠 点击这里给我发消息

  • 库存: 现货
可选包装 >>>
首页
  • 货号: ajcx29064
  • CAS: 1486-70-0
  • 别名: 3-O-甲基槲皮素
  • 分子式: C16H12O7
  • 分子量: 316.26
  • 纯度: >98%
  • 溶解度:
  • 储存: Store at -20°C
  • 库存: 现货

Background

3-O-methyl Quercetin is a flavone that has been found in C. balchaschensis and has diverse biological activities.1,2,3,4 It is an inhibitor of β-secretase (IC50 = 6.5 ?M).1 It scavenges DPPH radicals and superoxide anions in cell-free assays (IC50s = 14.17 and 17.39 ?M, respectively), as well as inhibits lipid peroxidation and hydrogen peroxide-induced neuronal cell death in primary rat cortical cells (IC50s = 19 and 3.5 ?M, respectively).2 3-O-methyl Quercetin inhibits poliovirus RNA synthesis in infected HeLa cells when used at concentrations of 2 and 20 ?g/ml.3 It also inhibits LPS-induced nitric oxide (NO) production in BV-2 microglia (IC50 = 3.8 ?M) and reduces LPS-induced increases in the levels of inducible nitric oxide synthase (iNOS) in BV-2 microglia.4


1.Zhumanova, K., Lee, G., Baiseitova, A., et al.Inhibitory mechanism of O-methylated quercetins, highly potent β-secretase inhibitors isolated from Caragana balchaschensis (Kom.) PojarkJ. Ethnopharmacol.272113936(2021) 2.Kim, S.H., Kumar, C.N., Kim, H.J., et al.Glucose-containing flavones—their synthesis and antioxidant and neuroprotective activitiesBioorg. Med. Chem. Lett.19(21)6009-6013(2009) 3.Castrillo, J.L., and Carrasco, L.Action of 3-methylquercetin on poliovirus RNA replicationJ. Virol.61(10)3319-3321(1987) 4.Kim, J.Y., Lim, H.J., and Ryu, J.-H.In vitro anti-inflammatory activity of 3-O-methyl-flavones isolated from Siegesbeckia glabrescensBioorg. Med. Chem. Lett.18(4)1511-1514(2008)

动态评分

0.0

没有评分数据
没有评价数据
一键回到顶部
展开 收缩
安捷凯在线客服