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  • Isoastilbin
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Isoastilbin

Isoastilbin,RhizomaSmilacisglabrae和Astragalusmembranaceus中的一种二氢黄酮醇糖苷化合物。Isoastilbin抑制葡萄糖基转移酶(GTase)的IC50值为54.3μg/mL,还抑制酪氨酸酶(tyrosinase)活性。Isoastilbin具有神经保护,抗氧化,抗微生物和抗凋亡的特性,并可用于阿尔茨海默氏病的研究。

原价
¥2175-5400
价格
1740-4320
Isoastilbin的二维码

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  • 库存: 现货
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  • 货号: ajcx29424
  • CAS: 54081-48-0
  • 别名: 异落新妇苷
  • 分子式: C21H22O11
  • 分子量: 450.39
  • 纯度: >98%
  • 溶解度:
  • 储存: Store at -20°C
  • 库存: 现货

Background

Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg/mL, and also inhibits tyrosinase activity. Isoastilbin shows neuroprotective, antioxidation, antimicrobial and anti-apoptotic properties and has the potential for Alzheimer's disease research[1][21][3].



[1]. Hong Yu, et al. Protective Roles of Isoastilbin Against Alz heimer's Disease via Nrf2-mediated Antioxidation and anti?apoptosis. Int J Mol Med. 2019 Mar;43(3):1406-1416. [2]. Harlinda Kuspradini, et al. Antimicrobial activity against Streptococcus sobrinus and glucosyltransferase inhibitory activity of taxifolin and some flavanonol rhamnosides from kempas (Koompassia malaccensis) extracts. J. Wood Sci., 2009, 55(4):308-13. [3]. Batubara, Irmanida, et al. Anti-acne and Tyrosinase Inhibition Properties of Taxifolin and Some Flavanonol Rhamnosides from Kempas. Wood Research Journal ,2010, 1(1):45-9.

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