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Mal-PEG1-acid是一种不可降解 (non-cleavable) 的含 1 个单元 PEG 的 ADC linker,可用于合成 抗体偶联药物 (ADC)。
Mal-PEG1-acid is a non-cleavable (1 unit PEG) ADC linker used in the synthesis of antibody-drug conjugates (ADCs)
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
[1]. Karpov AS, et al. Nicotinamide Phosphoribosyltransferase Inhibitor as a Novel Payload for Antibody-Drug Conjugates. ACS Med Chem Lett. 2018 Jun 28;9(8):838-842.
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