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  • (S)-O-Desmethyl Venlafaxine N-Oxide
(S)-O-Desmethyl Venlafaxine N-Oxide的可视化放大

(S)-O-Desmethyl Venlafaxine N-Oxide

(S)-O-DesmethylVenlafaxineN-Oxide是(S)-O-DesmethylVenlafaxine的N-氧化物。O-DesmethylVenlafaxine是Venlafaxine的活性代谢产物。Venlafaxine是5-羟色胺-去甲肾上腺素再摄取抑制剂(SNRI)类的抗抑郁剂。

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¥1525-1525
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(S)-O-Desmethyl Venlafaxine N-Oxide的二维码

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  • 货号: ajcx29842
  • CAS: 1021934-03-1
  • 别名: S-O-去甲-文拉法辛N-氧化物
  • 分子式: C16H25NO3
  • 分子量: 279.37
  • 纯度: >98%
  • 溶解度:
  • 储存: Store at -20°C
  • 库存: 现货

Background

(S)-O-Desmethyl Venlafaxine N-Oxide is a N-oxyde of (S)-O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine[1]. Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class[2].



[1]. Lechoslaw A. Turski, et al. N-oxydes de venlafaxine et de o-desméthylvenlafaxine comme promédicaments. WO2009000797A1. [2]. Yijin Liu, et al. Development of an enantioselective assay for simultaneous separation of venlafaxine and O-desmethylvenlafaxine by micellar electrokinetic chromatography-tandem mass spectrometry: Application to the analysis of drug-drug interaction. J Chromatogr A. 2015 Nov 13;1420:119-28. [3]. F P Bymaste, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80.

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