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  • Dalbavancin hydrochloride
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Dalbavancin hydrochloride

A semisynthetic glycopeptide antibiotic

原价
¥600-13887
价格
480-11110
Dalbavancin hydrochloride的二维码

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  • 货号: ajcx30460
  • CAS: 2227366-51-8
  • 别名: 盐酸达巴万星; MDL-63397 hydrochloride; BI-397 hydrochloride
  • 分子式: C88H101Cl3N10O28
  • 分子量: 1853.15
  • 纯度: >98%
  • 溶解度: Water: 50 mg/mL (26.98 mM); DMSO: ≥ 24 mg/mL (12.95 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

Dalbavancin is a semisynthetic glycopeptide antibiotic.1 It inhibits the growth of Gram-positive bacteria in vitro, including S. pneumoniae, S. pyogenes, vancomycin-sensitive Enterococcus species, and various methicillin-resistant staphylococci (MIC50s = 0.03, ≤0.002, 0.13, and 0.03-0.13 mg/L, respectively). Dalbavancin increases survival in mouse models of infection with S. aureus and S. pneumoniae (ED50s = 0.08 and 0.56 mg/kg, respectively). This product is a mixture of five closely related components, dalbavancin A0, A1, B0, B1, and B2, with dalbavancin B0 being the major component (≥75%). Formulations containing dalbavancin have been used in the treatment of bacterial skin infections caused by Gram-positive bacteria.


1.Candiani, G., Abbondi, M., Borgonovi, M., et al.In-vitro and in-vivo antibacterial activity of BI 397, a new semi-synthetic glycopeptide antibioticJ. Antimicrob. Chemother.44(2)179-192(1999)

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