CDK-IN-6

CDK-IN-6，是一类吡唑并[1,5-a]嘧啶化合物，是一种具有抗癌活性的 CDK 抑制剂。

原价

￥1100-1100

价格

￥ 880-880

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库存: 现货

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产品引用

货号: ajcx33188
CAS: 779353-02-5
别名: (S)-2-(1-(3-乙基-7-((吡啶-3-基甲基)氨基)吡唑并[1,5-A]嘧啶-5-基)
分子式: C21H28N6O
分子量: 380.49
纯度: >98%
溶解度: DMSO : 50 mg/mL (131.41 mM; Need ultrasonic)
储存: Store at -20°C
库存: 现货

Background

CDK-IN-6, a class of pyrazolo[1,5-a]pyrimidine compound, is a CDK inhibitor with anticancer activities[1].

Individual CDK’s, such as, CDK1, CDK2, CDK3, CDK4, CDK5, CDK6 and CDK7, CDK8 and the like, perform distinct roles in cell cycle progression and can be classified as either G1, S, or G2M phase enzymes. Uncontrolled proliferation is a hallmark of cancer cells, and misregulation of CDK function occurs with high frequency in many important solid tumors[1].

[1]. Timothy Guzi, et al. Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors. US20040209878A1.

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信号通路

生命科学

有机化学

无机化学

材料科学

CDK-IN-6

CDK-IN-6详情

Background