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Stafia-1 is the first STAT5a inhibitor that inhibits STAT5a (IC50=22.2?μM, Ki=10.9?μM) with at least 9‐fold selectivity over STAT5b and higher selectivity against other STAT family members.
Stafia-1 is the first STAT5a inhibitor that inhibits STAT5a (IC50=22.2?μM, Ki=10.9?μM) with at least 9‐fold selectivity over STAT5b and higher selectivity against other STAT family members.
[1] Natarajan K, et al. Chemistry. 2020 Jan 2;26(1):148-154.
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