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[18F]AZD4694 Precursor 是合成 [18F] AZD4694的前体,用于合成 [18F] AZD4694。[18F] AZD4694 是一种淀粉样蛋白 -β 成像配体,对淀粉样蛋白 -β 斑块具有高亲和性。
[18F]AZD4694 Precursor is the precursor of [18F] AZD4694 for the synthesis of [18F] AZD4694, an amyloid-β imaging ligand with high affinity for amyloid-β plaques[1].
18F-AZD4694 is an amyloid-β imaging ligand with high affinity for amyloid-β plaques. 18F-AZD4694 is a high affinity (Kd= 2.3 nM) radioligand for imaging amyloid-β plaques that displays lower white matter binding compared to other fluorinated amyloid-PET tracers, enabling easier visual reads[1].
[1]. Therriault J, et al. Determining Amyloid-β Positivity Using 18F-AZD4694 PET Imaging. J Nucl Med. 2021;62(2):247-252.
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