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Background:
JWH 071 is a synthetic cannabinoid (CB) which binds the central CB1 receptor (Ki = 1340 nM) with higher affinity than the peripheral CB2 receptor (Ki = 2940 nM).[1] [2] The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic purposes.
Reference:
[1]. Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug Alcohol Depend. 60(2), 133-140 (2000).
[2]. Wiley, J.L., Compton, D.R., Dai, D., et al. Structure-activity relationships of indole- and pyrrole-derived cannabinoids. J. Pharmacol. Exp. Ther. 285(3), 995-1004 (1998).
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