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  • 5'-deoxy-5-Fluorocytidine
5'-deoxy-5-Fluorocytidine的可视化放大

5'-deoxy-5-Fluorocytidine

An intermediate metabolite of capecitabine

原价
¥550-1487
价格
440-1190
5'-deoxy-5-Fluorocytidine的二维码

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  • 库存: 现货
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  • 货号: ajci69248
  • CAS: 66335-38-4
  • 别名: 5'-脱氧-5-氟胞苷
  • 分子式: C9H12FN3O4
  • 分子量: 245.2
  • 纯度: >98%
  • 溶解度: DMF: 10 mg/ml,DMSO: 20 mg/ml,PBS (pH 7.2): 10 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

5'-deoxy-5-Fluorocytidine is an intermediate metabolite of the DNA synthesis inhibitor capecitabine . Capecitabine is converted by carboxylesterase to 5'-deoxy-5-fluorocytidine in the liver, then by cytidine deaminase to 5'-deoxy-5-fluorouridine in the liver and tumor tissues, and finally, by thymidine phosphorylase to 5-fluorouracil in tumors. The cytotoxicity of this intermediate occurs only after conversion to 5-fluorouracil.

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