现货大促销，价格低至8折起，量大更优惠，详细咨询客服
安捷凯生物医药，安捷凯化学
全部分类
全部分类
  1. 首页
  2. CDK
  3. CDK/CRK Inhibitor
  • CDK/CRK Inhibitor
CDK/CRK Inhibitor的可视化放大

CDK/CRK Inhibitor

A CDK/CRK-specific kinase inhibitor

原价
￥3112-10787
价格
￥ 2490-8630
CDK/CRK Inhibitor的二维码

所有产品仅用于科学研究，我们不为任何个人用途提供产品和服务

询价有惊喜，量大更优惠 点击这里给我发消息

  • 库存: 现货
可选包装 >>>
首页
  • 货号: ajci70676
  • CAS: 784211-09-2
  • 别名: Cdk7 Inhibitor IV, Cyclin-dependent kinase 7 Inhibitor IV, Cyclin-dependent kinase/CDK-related kinase Inhibitor, RGB-286147
  • 分子式: C23H22Cl2N4O3
  • 分子量: 473.4
  • 纯度: >98%
  • 溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS(pH 7.2) (1:4): 0.2 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

CDK/CRK inhibitor is an inhibitor of cyclin-dependent kinases (CDK) and CDK-related kinases (CRK) with IC50 values ranging from 9-839 nM in vitro. It is selective, exhibiting less than 20% inhibition of 60 non-CDK/CRK kinases, at a concentration of 1 μM. CDK/CRK inhibitor induces cell cycle arrest in the G1 phase, endoreduplication, and apoptosis in HCT116 cells. It exhibits broad anti-tumor activity with an average GI50 value of <10 nM for 60 tumorigenic cell lines. It also inhibits growth of non-cycling HCT116 cells with an IC50 value of 40 nM.

动态评分

0.0

没有评分数据
没有评价数据
一键回到顶部
展开 收缩
安捷凯在线客服