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  2. RIP kinase
  3. GSK-J2 (sodium salt)
  • GSK-J2 (sodium salt)
GSK-J2 (sodium salt)的可视化放大

GSK-J2 (sodium salt)

A negative control compound for GSK-J1

原价
￥575-15662
价格
￥ 460-12530
GSK-J2 (sodium salt)的二维码

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  • 库存: 现货
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  • 货号: ajci71826
  • CAS: 2108665-15-0
  • 别名:
  • 分子式: C22H23N5O2?Na
  • 分子量: 412.4
  • 纯度: >98%
  • 溶解度: Soluble in DMSO
  • 储存: Store at -20°C
  • 库存: 现货

Background

The histone H3 lysine 27 (H3K27) demethylase JMJD3 plays important roles in the transcriptional regulation of cell differentiation, development, the inflammatory response, and cancer. GSK-J2 is a pyridine regio-isomer of GSK-J1 which poorly inhibits JMJD3 (IC50 > 100 μM), making it an appropriate negative control for in vitro studies involving GSK-J1. For in vivo research, cell-permeable prodrug forms of GSK-J1 and GSK-J2 are available as GSK-J4 and GSK-J5 , respectively. See the Structural Genomics Consortium (SGC) website for more information.

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