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安捷凯生物医药，安捷凯化学
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  3. Leucinostatin A
  • Leucinostatin A
Leucinostatin A的可视化放大

Leucinostatin A

A fungal metabolite with diverse biological activities

原价
￥3662-14550
价格
￥ 2930-11640
Leucinostatin A的二维码

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  • 库存: 现货
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  • 货号: ajci72342
  • CAS: 76600-38-9
  • 别名: 白灰制菌素A,Antibiotic P168
  • 分子式: C62H111N11O13
  • 分子量: 1218.6
  • 纯度: >98%
  • 溶解度: DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
  • 储存: Store at -20°C
  • 库存: 现货

Background

Leucinostatin A is a fungal metabolite originally isolated from P. lilacinus with diverse biological activities. It is active against P. oryzae, B. cinera, P. chrysogenum, X. oryzae, S. cerevisiae, and C. albicans fungi and B. subtilis, S. aureus, S. lutea, and M. phlei bacteria in a disc assay. Leucinostatin A (0.1-1 μg/ml) reduces T cell activation induced by phorbol 12-myristate 13-acetate or an anti-CD3 antibody in a concentration-dependent manner. It inhibits proliferation of DU145 prostate cancer cells co-cultured with PrSC stromal cells in vitro (IC50 = 0.045 μg/ml).

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