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An insecticide
Spinetoram is an insecticide and a semisynthetic derivative of the insecticide spinosad . Spinetoram is a mixture of 3'-ethyl-5,6-dihydrospinosyn J and 3'-ethoxy-spinosyn L . It induces mortality in H. armigera third, fourth, and fifth instar larvae when administered in the diet at 0.19 and 0.36 mg/kg and decreases pupal survival and adult emergence in surviving larvae. It also induces mortality of wild-type D. melanogaster but not D. melanogaster containing a genetic mutation in the Dα6 subunit of the nicotinic acetylcholine receptor (nAChR; LC50s = 0.025 and 4.4 µg/cm2, respectively, administered in the diet). Formulations containing spinetoram have been used as insecticides in agriculture.
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