安捷凯在线客服
- 客服:
- 电话: 13061953619
- 微信:
1-Ethynylnaphthalene 是细胞色素 P450 1B1 的选择性抑制剂。
1-Ethynylnaphthalene is a selective inhibitor of cytochrome P450 1B1.
1-Ethynylnaphthalene, selective inhibitor of cytochrome P450 IB1, does not affect 2-hydroxylation but inhibits 4-hydroxylation by 38%. At higher concentrations, 1-Ethynylnaphthalene inhibits 2-hydroxylation of 2-Hydroxylation of estradiol (E2) by ~30% and 4-hydroxylation of E2 by up to 80%[1].
[1]. Liehr JG, et al. 4-Hydroxylation of estradiol by human uterine myometrium and myoma microsomes: implications for the mechanism of uterine tumorigenesis. Proc Natl Acad Sci U S A. 1995 Sep 26;92(20):9220-4.
动态评分
0.0