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安捷凯生物医药，安捷凯化学
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  2. HSP (Heat shock proteins)
  3. JG-98
  • JG-98
JG-98的可视化放大

JG-98

JG-98 is an allosteric inhibitor of Hsp70 that binds tightly to a deep pocket that is conserved in members of the Hsp70 family. JG-98 induces classical apoptosis features, including morphological changes consistent with programmed cell death and positive

原价
￥3775-17625
价格
￥ 3020-14100
JG-98的二维码

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  • 库存: 现货
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  • 货号: ajce53510
  • CAS: 1456551-16-8
  • 别名: 3-苄基-2-((Z)-((E)-5-(6-氯-3-甲基苯并[D]噻唑-2(3H)-亚基)-3-乙基-4-氧代噻唑啉-2-亚基)甲基)噻唑-3-鎓氯化物
  • 分子式: C24H21Cl2N3OS3
  • 分子量: 534.54
  • 纯度: >98%
  • 溶解度: DMSO : 5 mg/mL (9.35 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

JG-98 is an allosteric inhibitor of Hsp70 that binds tightly to a deep pocket that is conserved in members of the Hsp70 family. JG-98 induces classical apoptosis features, including morphological changes consistent with programmed cell death and positive annexin staining. JG-98 exhibits anticancer activity.


[1] Julia A. Yaglom, et al. Scientific Reports. 2018, volume 8, Article number: 3010.

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