IMR-1A

IMR-1A, an acid metabolite of IMR-1, is a potent inhibitor of Notch with IC50 of 0.5 μM and Kd of 2.9 μM. IMR-1A exhibits anti-tumor activity.

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￥ 0-14530

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Background

IMR-1A, an acid metabolite of IMR-1, is a potent inhibitor of Notch with IC50 of 0.5 μM and Kd of 2.9 μM. IMR-1A exhibits anti-tumor activity.

[1] Luisana Astudillo, et al. Cancer Res. 2016 Jun 15;76(12):3593-603.

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