Aerobic glycolysis/The Warburg effect

有氧糖酵解/Warburg 效应

英文解释

Aerobic glycolysis/The Warburg effect is the increasing utilization of glycolysis rather than oxidative phosphorylation by tumour cells for their energy requirements under physiological oxygen conditions. This effect has been the basis for much speculation on the survival advantage of tumour cells, tumourigenesis and the microenvironment of tumours.

中文解释

有氧糖酵解/Warburg 效应是肿瘤细胞在生理氧条件下增加对糖酵解的利用而不是氧化磷酸化以满足其能量需求。这种效应是许多关于肿瘤细胞生存优势、肿瘤发生和肿瘤微环境的推测的基础。

参考文献

[1]. Bhattacharya B, et al. The Warburg effect and drug resistance. Br J Pharmacol. 2016 Mar;173(6):970-9.