Aldehyde dehydrogenase (ALDH)

醛脱氢酶

英文解释

Aldehyde dehydrogenase (ALDH) family is cytosolic isoenzyme responsible for oxidizing intracellular aldehydes, thus contributing to the oxidation of retinol to retinoic acid in early stem cell differentiation.Aldehyde dehydrogenase 1 is a tumor stem cell-associated marker in lung cancer.

中文解释

醛脱氢酶 (ALDH) 家族是一种胞质同工酶，负责氧化细胞内醛类物质，从而在早期干细胞分化过程中促进视黄醇氧化为视黄酸。乙醛脱氢酶 1 是肺癌肿瘤干细胞相关标志物。

参考文献

[1]. Jiang F, et al. Aldehyde dehydrogenase 1 is a tumor stem cell-associated marker in lung cancer. Mol Cancer Res. 2009 Mar;7(3):330-8.