C-terminal binding protein 2 (CtBP2)

C-末端结合蛋白 2

英文解释

C-terminal binding protein 2 (CtBP2) is an ovarian cancer oncogene that regulates gene expression program by modulating HDAC?activity. CtBP2 expression may be a surrogate indicator of cellular sensitivity to HDAC?inhibitors.

中文解释

C-末端结合蛋白 2 (CtBP2) 是一种通过调控 HDAC 活性来调控基因表达程序的卵巢癌癌基因。CtBP2 的表达可能是细胞对 HDAC 抑制剂敏感性的替代指标。

参考文献

[1]. Barroilhet L, et al. C-terminal binding protein-2 regulates response of epithelial ovarian cancer cells to histone deacetylase inhibitors. Oncogene. 2013 Aug 15;32(33):3896-903.