Damage-associated molecular molecules (DAMPs)

损伤相关分子模式

英文解释

Damage-associated molecular patterns (DAMPs) are endogenous danger molecules that are released from damaged or dying cells. DAMPs can activate the innate immune system by interacting with pattern recognition receptors (PRRs).

中文解释

损伤相关分子模式 (DAMP) 是从受损或垂死的细胞中释放出来的内源性危险分子。DAMP 可以通过与模式识别受体 (PRR) 发生相互作用来激活先天免疫系统。

参考文献

[1]. Roh JS, et al. Damage-Associated Molecular Patterns in Inflammatory Diseases. Immune Netw. 2018 Aug 13;18(4):e27.