Dihydropyrimidine dehydrogenase (DPD)

二氢嘧啶脱氢酶

英文解释

Dihydropyrimidine dehydrogenase (DPD) is an enzyme majorly involved in the metabolism of pyrimidines in the human body and has the same metabolising effect on 5-FU, a pyrimidine analogue.

中文解释

二氢嘧啶脱氢酶 (DPD) 是一种主要参与人体嘧啶代谢的酶，对嘧啶类似物 5-FU 具有相同的代谢作用。

参考文献

[1]. Sharma V, et al. Dihydropyrimidine dehydrogenase in the metabolism of the anticancer drugs. Cancer Chemother Pharmacol. 2019 Dec;84(6):1157-1166.