DNA topoisomerase I (topo I)

DNA 拓扑异构酶 I

英文解释

DNA topoisomerase I is an enzyme that cuts DNA strands. The DNA relaxation activity of topoisomerase I is dispensable for transcriptional repression.

中文解释

DNA 拓扑异构酶 I (topo I) 是一种能切断 DNA 链的酶。DNA 拓扑异构酶 I 的 DNA 弛豫活性对转录抑制是不可或缺的。

参考文献

[1]. Merino A, et al. DNA topoisomerase I is involved in both repression and activation of transcription. Nature. 1993 Sep 16;365(6443):227-32.