DNA topoisomerase II (topo II)

II 型 DNA 拓扑异构酶

英文解释

DNA topoisomerase II (topo II) are essential and ubiquitous enzymes that perform important intracellular roles in chromosome condensation and segregation, and in regulating DNA supercoiling.

中文解释

II 型 DNA 拓扑异构酶 (topo II) 是一种重要且普遍存在的酶，在染色体凝聚和分离以及调节DNA超卷曲中发挥着重要的细胞内作用。

参考文献

[1]. Collins TR, et al. Analysis of the eukaryotic topoisomerase II DNA gate: a single-molecule FRET and structural perspective. Nucleic Acids Res. 2009 Feb;37(3):712-20.