G-protein coupled receptors (GPCRs)

G 蛋白偶联受体

英文解释

G-protein coupled receptors (GPCRs) are the largest group of membrane receptor proteins. GPCRs comprise a large family of cell-surface receptors that regulate many cell functions, including cell proliferation, survival and motility. GPCRs also is a key player in tumour growth, angiogenesis and metastasis.

中文解释

G 蛋白偶联受体 (GPCR) 是最大的一组膜受体蛋白。GPCRs 包 含一大类细胞表面受体，可调节许多细胞功能，包括细胞增殖、存活和运动。GPCRs 也是肿瘤生长、血管生成和转移的关键参与者。

参考文献

[1]. Alexander Shpakov, et al. Allosteric Modulators of G Protein-Coupled Receptors. Int J Mol Sci. 2022 Mar 8;23(6):2934.
[2]. Robert T Dorsam, et al. G-protein-coupled receptors and cancer. Nat Rev Cancer. 2007 Feb;7(2):79-94.