Macrophage stimulating protein (MSP)

巨噬细胞刺激蛋白

英文解释

Macrophage stimulating protein (MSP), also known as macrophage stimulating 1 (MST1) and hepatocyte growth factor (HGF)-like protein, is an 80-kDa serum protein synthesized and secreted as a biologically inactive pro-MSP in the liver, and cleaved by serum protease to form active protein.

中文解释

巨噬细胞刺激蛋白 (MSP)，又称巨噬细胞刺激1 (MST1) 和肝细胞生长因子 (HGF) 样蛋白，是在肝脏中合成并分泌的一种 80 kDa 的血清蛋白，原作为一种生物活性不强的促 MSP，经血清蛋白酶切割形成活性蛋白。

参考文献

[1]. Jeong BC, et al. Macrophage-Stimulating Protein Enhances Osteoblastic Differentiation via the Recepteur d'Origine Nantais Receptor and Extracellular Signal-Regulated Kinase Signaling Pathway. J Bone Metab. 2020 Nov;27(4):267-279.