Major histocompatibility complex (MHC)/HLA proteins

主要组织相容性复合体 (MHC)/HLA 蛋白

英文解释

Major histocompatibility complex (MHC)/HLA proteins are mediators of the T-lymphocyte responses. MHC comprises a family of surface proteins that regulate the adaptive immune system. The HLA comprises HLA classes I, II, III, as well as extended classes I and II sub-regions. This region is highly polygenic and polymorphic.

中文解释

主要组织相容性复合体 (MHC)/HLA 蛋白是 T 淋巴细胞反应的介质。MHC 包含调节适应性免疫系统的表面蛋白家族。HLA 包括 HLA I、II、III 类以及扩展的 I 类和 II 区域。该区域是高度多基因和多态性的。

参考文献

[1]. Ryan Mokhtari, et al. The Major Histocompatibility Complex (MHC) in Schizophrenia: A Review. J Clin Cell Immunol. 2016 Dec;7(6):479.