Mitochondrial permeability transition pore (mPTP)

线粒体通透性过渡孔

英文解释

Mitochondrial permeability transition pore (mPTP), a transient channel on the inner mitochondrial membrane that opens under oxidative stress or high mitochondrial matrix calcium levels.

中文解释

线粒体通透性过渡孔 (mPTP) 是线粒体内膜上的一种短暂通道，在氧化应激或线粒体基质钙水平过高时打开。

参考文献

[1]. Alexander A Peterson, et al. Discovery and molecular basis of subtype-selective cyclophilin inhibitors. Nat Chem Biol. 2022 Sep 26.