Mouse double minute 2 homolog (MDM2)

鼠标双分钟 2 同系物 (MDM2)

英文解释

Mouse double minute 2 homolog (MDM2) is an E3 ubiquitin ligase, has been identified as an oncoprotein that mediates the ubiquitination and degradation of tumor suppressor p53.

中文解释

小鼠双分钟 2 同系物 (MDM2) 是一种 E3 泛素连接酶，已被鉴定为一种癌蛋白，可介导肿瘤抑制因子 p53 的泛素化和降解。

参考文献

[1]. Wang A, et al. Mouse Double Minute 2 Homolog-Mediated Ubiquitination Facilitates Forkhead Box P3 Stability and Positively Modulates Human Regulatory T Cell Function. Front Immunol. 2020 Jun 19;11:1087.