Oxygen-glucosedeprivation (OGD)

氧糖剥夺

英文解释

Oxygen-glucosedeprivation(OGD) is widely used as an in vitro model for stroke, showing similarities with the in vivo models of brain ischemia. In order to perform OGD, cell or tissue cultures, such as primary neurons or organotypic slices, and acutely prepared tissue slices are usually incubated in a glucose-free medium under a deoxygenated atmosphere, for example in a hypoxic chamber.

中文解释

氧糖剥夺 (OGD) 被广泛应用于脑卒中的体外模型，与脑缺血的体内模型有相似之处。为了进行 OGD，细胞或组织培养，如初级神经元或有机型切片，以及急性制备的组织切片通常在缺氧气氛下的无葡萄糖培养基中培养，例如在缺氧室中。

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