Oxytocin (OT)

催产素

英文解释

Oxytocin (OT) is a neuropeptide consisting of nine amino acids produced by the paraventricular and supraoptic nuclei of the hypothalamus. After OT synthesis the neuropeptide is transported and stored in the neurohypophysis where it is released into the circulation and to peripheral effects. Another pathway is whereby paraventricular nuclei have specific projections, which deliver Oxytocin to other structures in the brain including amygdala, hypothalamus, and hippocampus and nucleus accumbens. OT induces labor through increasing uterine tone and promoting uterine contractions. OT is also involved in maternal bonding, sexual behavior and affiliation.

中文解释

催产素 (OT) 是一种由下丘脑室旁核和视上核产生的九种氨基酸组成的神经肽。在 OT 合成后，神经肽被运输并储存在神经垂体中，被释放到循环中并产生外周效应。另一种途径是室旁核具有特定的投射，将催产素输送到大脑中的其他结构，包括杏仁核、下丘脑、海马和伏隔核。OT 通过增加子宫张力和促进子宫收缩来诱导分娩。OT 还涉及母体结合、性行为和从属关系。

参考文献

[1]. Waguih William Ishak, et al. Oxytocin role in enhancing well-being: a literature review. J Affect Disord. 2011 Apr;130(1-2):1-9.