Parathyroid hormone receptor 1 (PTHR1)

甲状旁腺激素受体 1

英文解释

Parathyroid hormone receptor 1 (PTHR1) is a family B G-protein-coupled receptor (GPCR) that regulates skeletal development, bone turnover and mineral ion homeostasis. PTHR1 is expressed primarily in bone, kidney and cartilage.

中文解释

甲状旁腺激素受体 1 (PTHR1) 是 B 族 G 蛋白偶联受体 (GPCR)，可调节骨骼发育、骨转换和矿物质离子稳态。PTHR1 主要在骨骼、肾脏和软骨中表达。

参考文献

[1]. Cheloha RW, et al. PTH receptor-1 signalling-mechanistic insights and therapeutic prospects. Nat Rev Endocrinol. 2015 Dec;11(12):712-24.