Phosphodiesterase 5A (PDE5A)

磷酸二酯酶 5A

英文解释

Phosphodiesterase 5A (PDE5A) is a cytoplasmic phosphodiesterase which specifically degrades cyclic guanosine monophosphate (cGMP), a cell signaling molecule that plays important roles in neuronal signaling and vascular smooth muscle contraction.

中文解释

磷酸二酯酶 5A (PDE5A) 是一种细胞质磷酸二酯酶，可特异性降解环磷酸鸟苷 (cGMP)，这是一种在神经元信号传导和血管平滑肌收缩中起重要作用的细胞信号分子。

参考文献

[1]. Julie Car?e Nordgaard, et al. Role of Ser102 and Ser104 as regulators of cGMP hydrolysis by PDE5A. PLoS One. 2014 Sep 23;9(9):e107627.