Platelet-derived growth factor receptor alpha (PDGFRA)

血小板衍生生长因子受体

英文解释

Platelet-derived growth factor receptor alpha (PDGFRA)?is a transmembrane protein with five immunoglobulin-like repeats in the extracellular domain and with a split intracellular tyrosine kinase domain. PDGFRA belongs to class III family of receptor tyrosine kinases (RTKs).

中文解释

血小板衍生生长因子受体 (PDGFRA) 是一种跨膜蛋白，在细胞外结构域具有 5 个免疫球蛋白样重复序列，在细胞内具有分裂的酪氨酸激酶结构域。PDGFRA 属于受体酪氨酸激酶 III 类家族。

参考文献

[1]. Martinho O,et al. Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas. Br J Cancer. 2009 Sep 15;101(6):973-82.