Polymyxin B (PMB)

多粘菌素 B

英文解释

Polymyxin B (PMB) is a decapeptide antibiotic characterized by a heptapeptide ring containing four 2,4-diaminobutyric acids. PMB is bactericidal to almost all gram-negative bacteria at rather low concentrations.

中文解释

多粘菌素 B (PMB) 是一种十肽抗生素，其特征在于含有四个 2,4-二氨基丁酸的七肽环。PMB 在相当低的浓度下对几乎所有的革兰氏阴性菌都有杀菌作用。

参考文献

[1]. R Daugelavicius, et al. Stages of polymyxin B interaction with the Escherichia coli cell envelope. Antimicrob Agents Chemother. 2000 Nov;44(11):2969-78.