Primary biliary cirrhosis (PBC)

原发性胆汁性肝硬化

英文解释

Primary biliary cirrhosis (PBC) is a chronic progressive cholestatic granulomatous, and destructive inflammatory lesion of small intralobular and septal bile ducts, which is likely to be caused by an autoimmune mechanism with a the presence of serum antimitochondrial antibodies and a potential tendency to progress to cirrhosis.

中文解释

原发性胆汁性肝硬化 (PBC) 是一种慢性进行性胆汁淤积性肉芽肿，小叶内和间隔小胆管的破坏性炎症病变，可能是由血清抗线粒体抗体存在的自身免疫机制引起的，并有向肝硬化发展的潜在趋势。

参考文献

[1]. Reshetnyak VI. Primary biliary cirrhosis: Clinical and laboratory criteria for its diagnosis. World J Gastroenterol. 2015 Jul 7;21(25):7683-708.