Primary sclerosing cholangitis (PSC)

原发性硬化性胆管炎

英文解释

Primary sclerosing cholangitis (PSC) is a rare cholestatic liver disease, characterized by multiple strictures and dilatations of the intra- and extrahepatic bile ducts, leading to progressive liver fibrosis, in 10-15% cholangiocarcinoma, and ultimately end-stage liver disease.

中文解释

原发性硬化性胆管炎 (PSC) 是一种罕见的胆汁淤积性肝病，其特征是肝内和肝外胆管的多重狭窄和扩张，导致进行性肝纤维化，在 10-15% 的胆管癌中，最终是终末期肝病。

参考文献

[1]. Prokopi? M, Beuers U. Management of primary sclerosing cholangitis and its complications: an algorithmic approach. Hepatol Int. 2021 Feb;15(1):6-20.