Small molecule drug conjugates (SMDCs)

小分子药物偶联物

英文解释

Small molecule drug conjugates (SMDCs) is an approach for targeted therapy. SMDCs use small molecules as the targeted ligand to release a potent cytotoxic agent selectively in the tumor microenvironment to enhance the therapeutic potential of anticancer drugs.

中文解释

小分子药物偶联物 (SMDC) 是一种靶向治疗方法。SMDCs 允许小分子作为靶向配体在肿瘤微环境中选择性地释放有效的细胞毒剂，以增强抗癌药物的治疗潜力。

参考文献

[1]. Zhuang C, et al. Small molecule-drug conjugates: A novel strategy for cancer-targeted treatment. Eur J Med Chem. 2019 Feb 1;163:883-895.