Ubiquitin-Proteasome Pathway (UPP)

泛素-蛋白酶体途径

英文解释

Ubiquitin-Proteasome Pathway (UPP) is a major intracellular protein degradation pathway. Ub is conjugated to proteins that are destined for degradation by an ATP-dependent process.

中文解释

泛素-蛋白酶体途径是一种主要的细胞内蛋白质降解途径，泛素 (Ub) 可与通过 ATP 依赖性过程降解的蛋白质结合。

参考文献

[1]. Lecker SH, et al. Protein degradation by the ubiquitin-proteasome pathway in normal and disease states. J Am Soc Nephrol. 2006 Jul;17(7):1807-19.